Is it important to have a huge list of target accounts?

Hey guys, do you think it’s important to have a huge list of accounts to target, or do you think it’s enough to have 5 big accounts with millions of follower ?

What’s your criteria for following? Blindly follow any of their followers, or do you have targeted rules?

I follow user that interacted with posts of target account. They have to have a profile pic, must be not private, and can’t have specific words in their bio/username/name (for example hack)